8WQ0

Cryo-EM structure of WIV1 spike glycoprotein (the closed state)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Spike glycoprotein	polymer	1271	140747.7	3	UniProt (U5WI05)	Bat SARS-like coronavirus WIV1
2	BA, CA, D, DA, EA... (b, c, D, d, e...)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	26	In PDB GlyTouCan (G42666HT)
3	AA, E, FA, I, JA... (a, E, f, I, j...)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	7	In PDB GlyTouCan (G15407YE)
4	AB, BB, CB, DB, EB... (C, A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	21	Chemie (NAG)

Sequence modifications

A, B, C: 1 - 1191 (UniProt: U5WI05)

PDB	External Database	Details
Pro 969	Lys 969	conflict
Pro 970	Val 970	conflict
Gly 1192	-	expression tag
Ser 1193	-	expression tag
Gly 1194	-	expression tag
Tyr 1195	-	expression tag
Ile 1196	-	expression tag
Pro 1197	-	expression tag
Glu 1198	-	expression tag
Ala 1199	-	expression tag
Pro 1200	-	expression tag
Arg 1201	-	expression tag
Asp 1202	-	expression tag
Gly 1203	-	expression tag
Gln 1204	-	expression tag
Ala 1205	-	expression tag
Tyr 1206	-	expression tag
Val 1207	-	expression tag
Arg 1208	-	expression tag
Lys 1209	-	expression tag
Asp 1210	-	expression tag
Gly 1211	-	expression tag
Glu 1212	-	expression tag
Trp 1213	-	expression tag
Val 1214	-	expression tag
Leu 1215	-	expression tag
Leu 1216	-	expression tag
Ser 1217	-	expression tag
Thr 1218	-	expression tag
Phe 1219	-	expression tag
Leu 1220	-	expression tag
Gly 1221	-	expression tag
Arg 1222	-	expression tag
Ser 1223	-	expression tag
Leu 1224	-	expression tag
Glu 1225	-	expression tag
Val 1226	-	expression tag
Leu 1227	-	expression tag
Phe 1228	-	expression tag
Gln 1229	-	expression tag
Gly 1230	-	expression tag
Pro 1231	-	expression tag
Gly 1232	-	expression tag
His 1233	-	expression tag
His 1234	-	expression tag
His 1235	-	expression tag
His 1236	-	expression tag
His 1237	-	expression tag
His 1238	-	expression tag
His 1239	-	expression tag
His 1240	-	expression tag
Ser 1241	-	expression tag
Ala 1242	-	expression tag
Trp 1243	-	expression tag
Ser 1244	-	expression tag
His 1245	-	expression tag
Pro 1246	-	expression tag
Gln 1247	-	expression tag
Phe 1248	-	expression tag
Glu 1249	-	expression tag
Lys 1250	-	expression tag
Gly 1251	-	expression tag
Gly 1252	-	expression tag
Gly 1253	-	expression tag
Ser 1254	-	expression tag
Gly 1255	-	expression tag
Gly 1256	-	expression tag
Gly 1257	-	expression tag
Gly 1258	-	expression tag
Ser 1259	-	expression tag
Gly 1260	-	expression tag
Gly 1261	-	expression tag
Ser 1262	-	expression tag
Ala 1263	-	expression tag
Trp 1264	-	expression tag
Ser 1265	-	expression tag
His 1266	-	expression tag
Pro 1267	-	expression tag
Gln 1268	-	expression tag
Phe 1269	-	expression tag
Glu 1270	-	expression tag
Lys 1271	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	422243.1
Branched	Number of molecules	33
	Total formula weight	15140.2
Non-Polymers*	Number of molecules	21
	Total formula weight	4645.4
All*	Total formula weight	442028.7

*Water molecules are not included.