8WPY
Cryo-EM structure of SARS-CoV-2 receptor-binding domain (RBD) complexed with CB6 mutant,S309, and S304 antibodies
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | S309 fab heavy chain | polymer | 239 | 25747.7 | 1 | Homo sapiens | ||
| 2 | B (B) | S309 fab light chain | polymer | 215 | 23291.8 | 1 | Homo sapiens | ||
| 3 | C (C) | CB6 fab mutant heavy chain | polymer | 231 | 24862.9 | 1 | Homo sapiens | ||
| 4 | D (D) | CB6 fab mutant light chain | polymer | 216 | 23559.1 | 1 | Homo sapiens | ||
| 5 | E (H) | S304 fab heavy chain | polymer | 232 | 24930.7 | 1 | Homo sapiens | ||
| 6 | F (L) | S304 fab light chain | polymer | 216 | 23457.0 | 1 | Homo sapiens | ||
| 7 | G (R) | Spike protein S1 | polymer | 229 | 25951.2 | 1 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 | |
| 8 | H (E) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) |
Sequence modifications
R: 319 - 541 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| His 542 | - | expression tag |
| His 543 | - | expression tag |
| His 544 | - | expression tag |
| His 545 | - | expression tag |
| His 546 | - | expression tag |
| His 547 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 171800.4 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 732.7 | |
| All* | Total formula weight | 172533.1 |
