8WP1
Cryo-EM structure of SUCR1 in complex with cis-epoxysuccinic acid and Gi proteins
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Succinate receptor 1 | polymer | 304 | 35128.4 | 1 | UniProt (Q9BXA5) Pfam (PF00001) | Homo sapiens (human) | |
| 2 | B (C) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 353 | 40313.9 | 1 | UniProt (P63096) Pfam (PF00503) | Homo sapiens (human) | Adenylate cyclase-inhibiting G alpha protein |
| 3 | C (D) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 338 | 37198.7 | 1 | UniProt (P62873) Pfam (PF00400) | Homo sapiens (human) | |
| 4 | D (E) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 56 | 6218.2 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 5 | E (A) | (2R,3S)-oxirane-2,3-dicarboxylic acid | non-polymer | 132.1 | 1 | Chemie (U9S) | |||
| 6 | F (A) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
C: 2 - 354 (UniProt: P63096)
| PDB | External Database | Details |
|---|---|---|
| Ala 203 | Gly 203 | engineered mutation |
| Ser 326 | Ala 326 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 118859.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 132.1 | |
| All* | Total formula weight | 118991.2 |
