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8WND

Crystal structure of Saccharomyces cerevisiae isoleucyl-tRNA synthetase in complex with tRNA(Ile) and isoleucine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, B)
isoleucine--tRNA ligasepolymer1080124213.42UniProt (A0A6A5Q0L4)
Pfam (PF00133)
Pfam (PF08264)
Pfam (PF19302)
UniProt (by SIFTS) (P09436)
Saccharomyces cerevisiae (baker's yeast)
2B, D
(T, R)
tRNA(Ile)polymer7724870.82Escherichia coli
3E, L
(A, B)
ISOLEUCINEnon-polymer131.22Chemie (ILE)
4F
(A)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
5G, H, I, J, K...
(A, B)
SULFATE IONnon-polymer96.19Chemie (SO4)
6Q, R, S, T
(A, T, B, R)
waterwater18.0208Chemie (HOH)
Sequence modifications
A, B: 1 - 1072 (UniProt: A0A6A5Q0L4)
PDBExternal DatabaseDetails
Leu 1073-expression tag
Glu 1074-expression tag
His 1075-expression tag
His 1076-expression tag
His 1077-expression tag
His 1078-expression tag
His 1079-expression tag
His 1080-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight298168.3
Non-Polymers*Number of molecules12
Total formula weight1189.0
All*Total formula weight299357.3
*Water molecules are not included.

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PDB entries from 2025-12-17

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