8WLZ
Cryo-EM structure of the WIV1 S-hACE2 complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Spike glycoprotein,Fibritin | polymer | 1271 | 140747.7 | 3 | UniProt (U5WI05) UniProt (A0A346FJN8) Pfam (PF16451) Pfam (PF09408) Pfam (PF01601) In PDB | Bat SARS-like coronavirus WIV1 | S glycoprotein,E2,Peplomer protein,Phage neck whiskers protein |
2 | D, G | Processed angiotensin-converting enzyme 2 | polymer | 603 | 69982.6 | 2 | UniProt (Q9BYF1) Pfam (PF01401) In PDB | Homo sapiens (human) | |
3 | E, F, H, I, J... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 13 | In PDB GlyTouCan (G42666HT) | |||
4 | M, N, S | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
5 | B, C, A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 21 | Chemie (NAG) |
Sequence modifications
A, B, C: 1 - 1191 (UniProt: U5WI05)
A, B, C: 1194 - 1219 (UniProt: A0A346FJN8)
D, G: 19 - 615 (UniProt: Q9BYF1)
PDB | External Database | Details |
---|---|---|
Pro 969 | Lys 969 | conflict |
Pro 970 | Val 970 | conflict |
Gly 1192 | - | linker |
Ser 1193 | - | linker |
PDB | External Database | Details |
---|---|---|
Leu 1220 | - | expression tag |
Gly 1221 | - | expression tag |
Arg 1222 | - | expression tag |
Ser 1223 | - | expression tag |
Leu 1224 | - | expression tag |
Glu 1225 | - | expression tag |
Val 1226 | - | expression tag |
Leu 1227 | - | expression tag |
Phe 1228 | - | expression tag |
Gln 1229 | - | expression tag |
Gly 1230 | - | expression tag |
Pro 1231 | - | expression tag |
Gly 1232 | - | expression tag |
His 1233 | - | expression tag |
His 1234 | - | expression tag |
His 1235 | - | expression tag |
His 1236 | - | expression tag |
His 1237 | - | expression tag |
His 1238 | - | expression tag |
His 1239 | - | expression tag |
His 1240 | - | expression tag |
Ser 1241 | - | expression tag |
Ala 1242 | - | expression tag |
Trp 1243 | - | expression tag |
Ser 1244 | - | expression tag |
His 1245 | - | expression tag |
Pro 1246 | - | expression tag |
Gln 1247 | - | expression tag |
Phe 1248 | - | expression tag |
Glu 1249 | - | expression tag |
Lys 1250 | - | expression tag |
Gly 1251 | - | expression tag |
Gly 1252 | - | expression tag |
Gly 1253 | - | expression tag |
Ser 1254 | - | expression tag |
Gly 1255 | - | expression tag |
Gly 1256 | - | expression tag |
Gly 1257 | - | expression tag |
Gly 1258 | - | expression tag |
Ser 1259 | - | expression tag |
Gly 1260 | - | expression tag |
Gly 1261 | - | expression tag |
Ser 1262 | - | expression tag |
Ala 1263 | - | expression tag |
Trp 1264 | - | expression tag |
Ser 1265 | - | expression tag |
His 1266 | - | expression tag |
Pro 1267 | - | expression tag |
Gln 1268 | - | expression tag |
Phe 1269 | - | expression tag |
Glu 1270 | - | expression tag |
Lys 1271 | - | expression tag |
PDB | External Database | Details |
---|---|---|
His 616 | - | expression tag |
His 617 | - | expression tag |
His 618 | - | expression tag |
His 619 | - | expression tag |
His 620 | - | expression tag |
His 621 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 562208.2 | |
Branched | Number of molecules | 16 |
Total formula weight | 7276.8 | |
Non-Polymers* | Number of molecules | 21 |
Total formula weight | 4645.4 | |
All* | Total formula weight | 574130.4 |