8WLM
Cryo-EM structure of human VMAT2 in presence of 5-HT, determined in an outward-facing conformation
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Synaptic vesicular amine transporter | polymer | 497 | 53823.2 | 1 | UniProt (Q05940) Pfam (PF07690) In PDB | Homo sapiens (human) | Monoamine transporter,Solute carrier family 18 member 2,Vesicular amine transporter 2,Vesicular Monoamine Transporter 2, VAT2 |
2 | A | SEROTONIN | non-polymer | 176.2 | 1 | Chemie (SRO) |
Sequence modifications
A: 1 - 474 (UniProt: Q05940)
PDB | External Database | Details |
---|---|---|
Ser 475 | - | expression tag |
Arg 476 | - | expression tag |
Leu 477 | - | expression tag |
Glu 478 | - | expression tag |
Glu 479 | - | expression tag |
Glu 480 | - | expression tag |
Leu 481 | - | expression tag |
Arg 482 | - | expression tag |
Arg 483 | - | expression tag |
Arg 484 | - | expression tag |
Thr 485 | - | expression tag |
Glu 486 | - | expression tag |
Gly 487 | - | expression tag |
Gly 488 | - | expression tag |
Ser 489 | - | expression tag |
Ser 490 | - | expression tag |
Asp 491 | - | expression tag |
Leu 492 | - | expression tag |
Glu 493 | - | expression tag |
Val 494 | - | expression tag |
Leu 495 | - | expression tag |
Phe 496 | - | expression tag |
Gln 497 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 53823.2 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 176.2 | |
All* | Total formula weight | 53999.4 |