8WHG

imine reductase mutant - M3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	6-phosphogluconate dehydrogenase NAD-binding protein	polymer	297	31023.1	8	UniProt (D9X416) Pfam (PF03446) Pfam (PF21761)	Streptomyces viridochromogenes	Imine reductase
2	I, J (B, E)	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	2	Chemie (NAP)
3	K, L, M, N, O... (A, B, C, D, E...)	water	water		18.0	236	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 297 (UniProt: D9X416)

PDB	External Database	Details
Arg 40	Thr 40	engineered mutation
Ser 73	Thr 73	engineered mutation
Tyr 97	Leu 97	engineered mutation
Gly 126	Ala 126	engineered mutation
Pro 127	Ile 127	engineered mutation
Trp 130	Asp 130	engineered mutation
Leu 131	Ile 131	engineered mutation
Arg 135	Ala 135	engineered mutation
Ile 137	Val 137	engineered mutation
Leu 214	Met 214	engineered mutation
Leu 217	Val 217	engineered mutation
Arg 221	Tyr 221	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	248184.9
Non-Polymers*	Number of molecules	2
	Total formula weight	1486.8
All*	Total formula weight	249671.7

*Water molecules are not included.