8WFY
The Crystal Structure of SHP2 from Biortus.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tyrosine-protein phosphatase non-receptor type 11 | polymer | 525 | 60181.9 | 2 | UniProt (Q06124) Pfam (PF00017) Pfam (PF00102) | Homo sapiens (human) | |
| 2 | C, D (A, B) | 6-(4-azanyl-4-methyl-piperidin-1-yl)-3-[2,3-bis(chloranyl)phenyl]pyrazin-2-amine | non-polymer | 352.3 | 2 | Chemie (5OD) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 424 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 525 (UniProt: Q06124)
| PDB | External Database | Details |
|---|---|---|
| Lys 2 | Thr 2 | conflict |
| Leu 41 | Phe 41 | conflict |
| Ser 513 | Phe 513 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 120363.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 704.5 | |
| All* | Total formula weight | 121068.4 |
