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8WFR

The Crystal Structure of PCSK9 from Biortus.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Proprotein convertase subtilisin/kexin type 9polymer12413905.61UniProt (Q8NBP7)
Pfam (PF05922)
Homo sapiens (human)
2B
(B)
Proprotein convertase subtilisin/kexin type 9polymer54057357.61UniProt (Q8NBP7)
Pfam (PF00082)
Pfam (PF18459)
Pfam (PF18464)
Pfam (PF18463)
Homo sapiens (human)
3C
(A)
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDnon-polymer238.31Chemie (EPE)
4D, F
(A)
1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
5E, G
(A, B)
GLYCEROLnon-polymer92.12Chemie (GOL)
6H, I
(A, B)
waterwater18.0409Chemie (HOH)
Sequence modifications
A: 31 - 152 (UniProt: Q8NBP7)
PDBExternal DatabaseDetails
Gly 29-expression tag
Gly 30-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight71263.2
Non-Polymers*Number of molecules5
Total formula weight546.6
All*Total formula weight71809.8
*Water molecules are not included.

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PDB entries from 2026-01-28

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