8WFH

Crystal structure of Omicron BA.4/5 in complex with a neutralizing antibody scFv D1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Spike protein S1	polymer	198	22352.2	1	UniProt (P0DTC2) Pfam (PF09408)	Severe acute respiratory syndrome coronavirus 2
2	B (E)	D1 scFv	polymer	232	25143.9	1		Homo sapiens

Sequence modifications

A: 1 - 198 (UniProt: P0DTC2)

PDB	External Database	Details
Asp 7	Gly 339	variant
Phe 39	Ser 371	variant
Pro 41	Ser 373	variant
Phe 43	Ser 375	variant
Ala 44	Thr 376	variant
Asn 73	Asp 405	variant
Ser 76	Arg 408	variant
Asn 85	Lys 417	variant
Lys 108	Asn 440	variant
Arg 120	Leu 452	variant
Asn 145	Ser 477	variant
Lys 146	Thr 478	variant
Ala 152	Glu 484	variant
Val 154	Phe 486	variant
Arg 166	Gln 498	variant
Tyr 169	Asn 501	variant
His 173	Tyr 505	variant

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	47496.1
All*	Total formula weight	47496.1

*Water molecules are not included.