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8WEA

Human L-type voltage-gated calcium channel Cav1.2 (Class II) in the presence of pinaverium at 3.2 Angstrom resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Voltage-dependent L-type calcium channel subunit alpha-1Cpolymer2201246851.31UniProt (Q13936)
Pfam (PF00520)
Pfam (PF16885)
Pfam (PF08016)
Pfam (PF16905)
Pfam (PF08763)
Homo sapiens (human)Calcium channel,L type,alpha-1 polypeptide,isoform 1,cardiac muscle,Voltage-gated calcium channel subunit alpha Cav1.2
2B
(D)
Voltage-dependent calcium channel subunit alpha-2/delta-1polymer1103124692.51UniProt (P54289)
Pfam (PF08399)
Pfam (PF00092)
Pfam (PF08473)
Homo sapiens (human)Voltage-gated calcium channel subunit alpha-2/delta-1
3C
(B)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched627.61In PDB
GlyTouCan (G47362BJ)
4D, F, G
(C, F, G)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.43In PDB
GlyTouCan (G42666HT)
5E
(E)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched830.81In PDB
GlyTouCan (G01361SX)
6H, K
(A, D)
CALCIUM IONnon-polymer40.12Chemie (CA)
7I
(A)
(3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-ennon-polymer544.81Chemie (9Z9)
8J
(A)
4-[(2-bromanyl-4,5-dimethoxy-phenyl)methyl]-4-[2-[2-[(1~{R},2~{S},5~{R})-6,6-dimethyl-2-bicyclo[3.1.1]heptanyl]ethoxy]ethyl]morpholin-4-iumnon-polymer511.51Chemie (WB9)
9L, M
(D)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight371543.7
BranchedNumber of molecules5
Total formula weight2731.6
Non-Polymers*Number of molecules6
Total formula weight1578.9
All*Total formula weight375854.2
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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