8WAA

Human transketolase soaked with donor ketose D-xylulose

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Transketolase	polymer	637	69647.5	2	UniProt (P29401) Pfam (PF00456) Pfam (PF02779) Pfam (PF02780)	Homo sapiens (human)
2	C, Q (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
3	D, R (A, B)	D-Glyceraldehyde	non-polymer		90.1	2	Chemie (3GR)
4	E, S (A, B)	2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE	non-polymer		484.4	2	Chemie (THD)
5	AA, BA, CA, DA, EA... (B, A)	1,2-ETHANEDIOL	non-polymer		62.1	25	Chemie (EDO)
6	HA, IA (A, B)	water	water		18.0	1196	Chemie (HOH)

Sequence modifications

A, B: 1 - 623 (UniProt: P29401)

PDB	External Database	Details
Leu 624	-	expression tag
Val 625	-	expression tag
Pro 626	-	expression tag
Arg 627	-	expression tag
Gly 628	-	expression tag
Ser 629	-	expression tag
Leu 630	-	expression tag
Glu 631	-	expression tag
His 632	-	expression tag
His 633	-	expression tag
His 634	-	expression tag
His 635	-	expression tag
His 636	-	expression tag
His 637	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	139294.9
Non-Polymers*	Number of molecules	31
	Total formula weight	2780.7
All*	Total formula weight	142075.6

*Water molecules are not included.