8W9I
Crystal structure of bacterial prolyl-tRNA synthetase in complex with inhibitor PAA-5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Proline--tRNA ligase | polymer | 579 | 64194.9 | 2 | UniProt (Q9I502) Pfam (PF00587) Pfam (PF04073) Pfam (PF03129) | Pseudomonas aeruginosa | |
| 2 | C, H (A, B) | (2~{S})-~{N}-[3-(4-azanylquinazolin-7-yl)phenyl]sulfonylpyrrolidine-2-carboxamide | non-polymer | 397.5 | 2 | Chemie (W2H) | |||
| 3 | D, I, J (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 4 | E, F, G, K, L... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 5 | N, O (A, B) | water | water | 18.0 | 138 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 571 (UniProt: Q9I502)
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | initiating methionine |
| Gly -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 128389.8 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1240.2 | |
| All* | Total formula weight | 129630.0 |
