8W9E

Cryo-EM structure of the Rpd3S-nucleosome complex from budding yeast in State 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Transcriptional regulatory protein SIN3	polymer	1536	175047.3	1	UniProt (P22579) Pfam (PF02671) Pfam (PF08295) Pfam (PF16879) In PDB	Saccharomyces cerevisiae (baker's yeast)
2	E, F	Transcriptional regulatory protein RCO1	polymer	684	78951.3	2	UniProt (Q04779) Pfam (PF00628) In PDB	Saccharomyces cerevisiae (baker's yeast)
3	B	Histone deacetylase RPD3	polymer	433	48962.0	1	UniProt (P32561) Pfam (PF00850) In PDB	Saccharomyces cerevisiae (baker's yeast)
4	C, D, G	Chromatin modification-related protein EAF3	polymer	401	45266.4	3	UniProt (Q12432) Pfam (PF11717) Pfam (PF22732) Pfam (PF05712) In PDB	Saccharomyces cerevisiae (baker's yeast)	ESA1-associated factor 3
5	a, e	Histone H3.1	polymer	136	15437.2	2	UniProt (P68431) Pfam (PF00125) In PDB	Homo sapiens (human)
6	b, f	Histone H4	polymer	103	11394.4	2	UniProt (P62805) Pfam (PF15511) In PDB	Homo sapiens (human)
7	c, g	Histone H2A type 1-B/E	polymer	130	14165.6	2	UniProt (P04908) Pfam (PF00125) Pfam (PF16211) In PDB	Homo sapiens (human)
8	d, h	Histone H2B type 1-K	polymer	126	13921.2	2	UniProt (O60814) Pfam (PF00125) In PDB	Homo sapiens (human)
9	i	5-DNA	polymer	147	45368.1	1		Homo sapiens (human)
10	j	3-DNA	polymer	147	45359.0	1		Homo sapiens (human)
11	E, B, F	ZINC ION	non-polymer		65.4	7	Chemie (ZN)
12	B	POTASSIUM ION	non-polymer		39.1	1	Chemie (K)

Contents of the asymmetric unit

Polymers	Number of chains	17
	Total formula weight	718274.9
Non-Polymers*	Number of molecules	8
	Total formula weight	497.0
All*	Total formula weight	718771.8

*Water molecules are not included.