8W8F
human co-transcriptional RNA capping enzyme RNGTT-CMTR1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (a) | mRNA-capping enzyme | polymer | 597 | 68655.7 | 1 | UniProt (O60942) Pfam (PF00782) Pfam (PF01331) Pfam (PF03919) | Homo sapiens (human) | HCAP1,HCE |
| 2 | B (b) | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 | polymer | 835 | 95454.8 | 1 | UniProt (Q8N1G2) Pfam (PF01585) Pfam (PF01728) | Homo sapiens (human) | Cap methyltransferase 1,Cap1 2'O-ribose methyltransferase 1,MTr1,hMTr1,FtsJ methyltransferase domain-containing protein 2,Interferon-stimulated gene 95 kDa protein,ISG95 |
| 3 | C (A) | DNA-directed RNA polymerase subunit | polymer | 1970 | 217450.1 | 1 | UniProt (A0A8D1DPV6) Pfam (PF04997) Pfam (PF05001) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) Pfam (PF04992) Pfam (PF04990) | Sus scrofa (pig) | |
| 4 | D (B) | DNA-directed RNA polymerase subunit beta | polymer | 1174 | 134041.4 | 1 | UniProt (A0A4X1TVZ5) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF04566) Pfam (PF04567) Pfam (PF00562) Pfam (PF04560) UniProt (by SIFTS) (I3LGP4) | Sus scrofa (pig) | |
| 5 | E (C) | DNA-directed RNA polymerase II subunit RPB3 | polymer | 271 | 30997.6 | 1 | UniProt (A0A481DF93) Pfam (PF01193) Pfam (PF01000) UniProt (by SIFTS) (I3LCH3) | Sus scrofa (pig) | |
| 6 | F (D) | DNA-directed RNA polymerase II subunit RPB4 | polymer | 142 | 16331.3 | 1 | UniProt (A0A481BYI6) Pfam (PF03874) UniProt (by SIFTS) (A0A4X1VM56) | Sus scrofa (pig) | DNA-directed RNA polymerase II subunit RPB4 isoform X1 |
| 7 | G (E) | DNA-directed RNA polymerase II subunit E | polymer | 210 | 24644.3 | 1 | UniProt (A0A4X1VTX4) Pfam (PF03871) Pfam (PF01191) UniProt (by SIFTS) (I3LSI7) | Sus scrofa (pig) | RPB5 homolog |
| 8 | H (F) | DNA-directed RNA polymerase II subunit F | polymer | 127 | 14477.0 | 1 | UniProt (A0A4X1VEK9) Pfam (PF01192) | Sus scrofa (pig) | DNA-directed RNA polymerases I,II,and III subunit RPABC2,RPB6 homolog |
| 9 | I (G) | DNA-directed RNA polymerase II subunit RPB7 | polymer | 172 | 19314.3 | 1 | UniProt (A0A4X1VKG7) Pfam (PF03876) Pfam (PF00575) | Sus scrofa (pig) | |
| 10 | J (H) | DNA-directed RNA polymerases I, II, and III subunit RPABC3 | polymer | 150 | 17162.3 | 1 | UniProt (I3LCB2) Pfam (PF03870) | Sus scrofa (pig) | |
| 11 | K (I) | DNA-directed RNA polymerase II subunit RPB9 | polymer | 125 | 14541.2 | 1 | UniProt (P60899) Pfam (PF02150) Pfam (PF01096) | Sus scrofa (pig) | RNA polymerase II subunit B9,DNA-directed RNA polymerase II subunit I,RNA polymerase II 14.5 kDa subunit,RPB14.5 |
| 12 | L (J) | DNA-directed RNA polymerases I, II, and III subunit RPABC5 | polymer | 67 | 7655.1 | 1 | UniProt (A0A493TD97) Pfam (PF01194) UniProt (by SIFTS) (A0A8W4F9W9) | Sus scrofa (pig) | |
| 13 | M (K) | DNA-directed RNA polymerase II subunit RPB11-a | polymer | 117 | 13310.3 | 1 | UniProt (F1RKE4) Pfam (PF13656) | Sus scrofa (pig) | |
| 14 | N (L) | RPB12 | polymer | 58 | 7018.2 | 1 | UniProt (A0A4X1TRS6) Pfam (PF03604) | Sus scrofa (pig) | |
| 15 | O (N) | DNA (36-MER) | polymer | 48 | 14932.5 | 1 | Homo sapiens | ||
| 16 | P (P) | RNA (5'-R(P*GP*AP*GP*AP*GP*AP*GP*GP*GP*AP*AP*CP*CP*CP*AP*CP*U)-3') | polymer | 17 | 5528.4 | 1 | Homo sapiens | ||
| 17 | Q (T) | DNA (45-MER) | polymer | 48 | 14672.3 | 1 | Homo sapiens | ||
| 18 | R (Y) | Transcription elongation factor SPT4 | polymer | 121 | 13508.5 | 1 | UniProt (P63272) Pfam (PF06093) | Homo sapiens (human) | hSPT4,DRB sensitivity-inducing factor 14 kDa subunit,DSIF p14,DRB sensitivity-inducing factor small subunit,DSIF small subunit |
| 19 | S (Z) | Transcription elongation factor SPT5 | polymer | 1087 | 121145.5 | 1 | UniProt (O00267) Pfam (PF11942) Pfam (PF03439) Pfam (PF00467) | Homo sapiens (human) | hSPT5,DRB sensitivity-inducing factor 160 kDa subunit,DSIF p160,DRB sensitivity-inducing factor large subunit,DSIF large subunit,Tat-cotransactivator 1 protein,Tat-CT1 protein |
| 20 | T (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 21 | AA, CA, U, V, W... (L, Y, A, B, C...) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 22 | BA (P) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) |
Sequence modifications
Y: 1 - 117 (UniProt: P63272)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 19 |
| Total formula weight | 850840.8 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1070.8 | |
| All* | Total formula weight | 851911.5 |
