8W86

HLA-DQ2.5-B/C hordein peptide in complex with DQN0385AE02

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (A, E)	DQN0385AE02 Fab heavy chain	polymer	223	23846.6	2		Homo sapiens
2	B, F (B, F)	DQN0385AE02 Fab light chain	polymer	213	23397.1	2		Homo sapiens
3	C, G (C, G)	HLA class II histocompatibility antigen, DQ alpha 1 chain	polymer	189	21396.9	2	UniProt (P01909) Pfam (PF00993) Pfam (PF07654)	Homo sapiens (human)	DC-1 alpha chain,DC-alpha,HLA-DCA,MHC class II DQA1
4	D, H (D, H)	MHC class II HLA-DQ-beta-1 - B/C hordein peptide chimeric protein	polymer	230	26299.4	2	UniProt (O19712) Pfam (PF00969) Pfam (PF07654)	Homo sapiens
5	I, J (C, G)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
6	K, L, M, N, O... (A, B, C, D, E...)	water	water		18.0	352	Chemie (HOH)

Sequence modifications

C, G: 1 - 183 (UniProt: P01909)

PDB	External Database	Details
Ser 47	Cys 70	engineered mutation
Leu 184	-	expression tag
Glu 185	-	expression tag
Val 186	-	expression tag
Leu 187	-	expression tag
Phe 188	-	expression tag
Gln 189	-	expression tag

D, H: -3 - 983 (PDB: 8W86)

PDB	External Database	Details
Gly 984	-	linker
Ser 985	-	linker
Gly 986	-	linker
Gly 987	-	linker
Gly 988	-	linker
Gly 989	-	linker
Ser 990	-	linker
Ile 991	-	linker
Glu 992	-	linker
Gly 993	-	linker
Arg 994	-	linker
Gly 995	-	linker
Ser 996	-	linker
Gly 997	-	linker
Gly 998	-	linker
Gly 999	-	linker
Ser 1000	-	linker

D, H: 1001 - 1190 (UniProt: O19712)

PDB	External Database	Details
Leu 1191	-	expression tag
Glu 1192	-	expression tag
Val 1193	-	expression tag
Leu 1194	-	expression tag
Phe 1195	-	expression tag
Gln 1196	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	189880.1
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	190322.5

*Water molecules are not included.