8W6C

CryoEM structure of NaDC1 with Citrate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Solute carrier family 13 member 2	polymer	605	65934.3	2	UniProt (Q13183) Pfam (PF00939)	Homo sapiens (human)	Na(+)/dicarboxylate cotransporter 1,NaDC-1,Renal sodium/dicarboxylate cotransporter
2	C, D, J, K (A, B)	SODIUM ION	non-polymer		23.0	4	Chemie (NA)
3	E, G (A)	CHOLESTEROL HEMISUCCINATE	non-polymer		486.7	2	Chemie (Y01)
4	F, L (A, B)	CITRIC ACID	non-polymer		192.1	2	Chemie (CIT)
5	H, I (A, B)	1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE	non-polymer		705.0	2	Chemie (3PH)
6	M, N (A, B)	water	water		18.0	2	Chemie (HOH)

Sequence modifications

A, B: 1 - 592 (UniProt: Q13183)

PDB	External Database	Details
Met -12	-	initiating methionine
Ala -11	-	expression tag
Asp -10	-	expression tag
Tyr -9	-	expression tag
Lys -8	-	expression tag
Asp -7	-	expression tag
Asp -6	-	expression tag
Asp -5	-	expression tag
Asp -4	-	expression tag
Lys -3	-	expression tag
Ser -2	-	expression tag
Gly -1	-	expression tag
Arg 0	-	expression tag
Val 550	Ile 550	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	131868.5
Non-Polymers*	Number of molecules	10
	Total formula weight	2859.7
All*	Total formula weight	134728.2

*Water molecules are not included.