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8W5C

Crystal structure of FGFR4 kinase domain in complex with 8K

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Fibroblast growth factor receptor 4polymer30033672.92UniProt (P22455)
Pfam (PF07714)
Homo sapiens (human)
2C, D
(A, B)
N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-5-methanoyl-6-[(4-methylpiperazin-1-yl)methyl]-1-propan-2-yl-pyrrolo[3,2-b]pyridine-3-carboxamidenon-polymer518.62Chemie (VZO)
3E, F
(A, B)
waterwater18.0168Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight67345.8
Non-Polymers*Number of molecules2
Total formula weight1037.2
All*Total formula weight68383.0
*Water molecules are not included.

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PDB entries from 2025-07-02

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