8W3U

Structure of Epimerase Mth373 from the thermophilic pseudomurein-containing methanogen Methanothermobacter thermautotrophicus

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	dTDP-glucose 4,6-dehydratase related protein	polymer	337	40036.2	1	UniProt (O26473) Pfam (PF01370)	Methanothermobacter thermautotrophicus str. Delta H
2	B (B)	dTDP-glucose 4,6-dehydratase related protein	polymer	337	40051.2	1	UniProt (O26473) Pfam (PF01370)	Methanothermobacter thermautotrophicus str. Delta H
3	C, M (A, B)	URIDINE-5'-DIPHOSPHATE	non-polymer		404.2	2	Chemie (UDP)
4	D, N (A, B)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
5	E, F, G, H, I... (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	11	Chemie (EDO)
6	J, K, U (A, B)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
7	L, V (A, B)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
8	W, X (A, B)	water	water		18.0	432	Chemie (HOH)

Sequence modifications

A: 1 - 313 (UniProt: O26473)

PDB	External Database	Details
Tyr -23	-	expression tag
Pro -22	-	expression tag
Val -21	-	expression tag
Ala -20	-	expression tag
Ile -19	-	expression tag
Leu -18	-	expression tag
Leu -17	-	expression tag
Asp -16	-	expression tag
Ala -15	-	expression tag
Leu -14	-	expression tag
Tyr -13	-	expression tag
Trp -12	-	expression tag
Glu -11	-	expression tag
His -10	-	expression tag
Asp -9	-	expression tag
Lys -8	-	expression tag
Leu -7	-	expression tag
Glu -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

B: 1 - 313 (UniProt: O26473)

PDB	External Database	Details
Tyr -23	-	expression tag
Pro -22	-	expression tag
Val -21	-	expression tag
Ala -20	-	expression tag
Ile -19	-	expression tag
Leu -18	-	expression tag
Leu -17	-	expression tag
Asp -16	-	expression tag
Ala -15	-	expression tag
Leu -14	-	expression tag
Tyr -13	-	expression tag
Trp -12	-	expression tag
Glu -11	-	expression tag
His -10	-	expression tag
Asp -9	-	expression tag
Lys -8	-	expression tag
Leu -7	-	expression tag
Glu -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	80087.3
Non-Polymers*	Number of molecules	20
	Total formula weight	2961.7
All*	Total formula weight	83049.1

*Water molecules are not included.