8W3T
Crystal Structure of Enterovirus 68 3C Protease with GC376 at 1.98 Angstroms
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Genome polyprotein | polymer | 190 | 21106.0 | 1 | UniProt (A1E4A3) Pfam (PF00548) | enterovirus D68 | |
| 2 | B (A) | N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide | non-polymer | 405.5 | 1 | Chemie (UED) | |||
| 3 | C (A) | water | water | 18.0 | 142 | Chemie (HOH) |
Sequence modifications
A: 1 - 182 (UniProt: A1E4A3)
| PDB | External Database | Details |
|---|---|---|
| Ala 183 | - | expression tag |
| Lys 184 | - | expression tag |
| His 185 | - | expression tag |
| His 186 | - | expression tag |
| His 187 | - | expression tag |
| His 188 | - | expression tag |
| His 189 | - | expression tag |
| His 190 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21106.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 405.5 | |
| All* | Total formula weight | 21511.5 |
