8W3M
Crystal Structure of Enterovirus 68 3C Protease with AG7404 at 1.97 Angstroms
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peptidase C3 | polymer | 190 | 21191.0 | 1 | UniProt (A1E4A3) Pfam (PF00548) | enterovirus D68 | |
| 2 | B (A) | ethyl (4R)-4-({(2S)-2-[3-{[(5-methyl-1,2-oxazol-3-yl)carbonyl]amino}-2-oxopyridin-1(2H)-yl]pent-4-ynoyl}amino)-5-[(3S)-2-oxopyrrolidin-3-yl]pentanoate | non-polymer | 525.6 | 1 | Chemie (XNV) | |||
| 3 | C, D, E, F, G... (A) | SODIUM ION | non-polymer | 23.0 | 10 | Chemie (NA) | |||
| 4 | M (A) | water | water | 18.0 | 154 | Chemie (HOH) |
Sequence modifications
A: 1 - 183 (UniProt: A1E4A3)
| PDB | External Database | Details |
|---|---|---|
| Arg 184 | - | expression tag |
| His 185 | - | expression tag |
| His 186 | - | expression tag |
| His 187 | - | expression tag |
| His 188 | - | expression tag |
| His 189 | - | expression tag |
| His 190 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21191.0 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 755.5 | |
| All* | Total formula weight | 21946.5 |
