8W31
Crystal structure of parkin (R0RB):2pUb with activator compound
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | E3 ubiquitin-protein ligase parkin | polymer | 240 | 26406.2 | 1 | UniProt (Q9JK66) Pfam (PF17976) Pfam (PF17978) In PDB | Rattus norvegicus (Norway rat) | Parkin RBR E3 ubiquitin-protein ligase |
| 2 | B, C | Ubiquitin | polymer | 75 | 8599.8 | 2 | UniProt (P0CG47) Pfam (PF00240) In PDB | Homo sapiens (human) | |
| 3 | A | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 4 | A | (S)-1-(6-benzyl-3-(4-(1,2,3,4-tetrahydroquinoline-1-carbonyl)phenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-5(4H)-yl)ethan-1-one | non-polymer | 490.6 | 1 | Chemie (A1AE9) | |||
| 5 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
A: 145 - 379 (UniProt: Q9JK66)
| PDB | External Database | Details |
|---|---|---|
| Gly 140 | - | expression tag |
| Pro 141 | - | expression tag |
| Leu 142 | - | expression tag |
| Gly 143 | - | expression tag |
| Ser 144 | - | expression tag |
| Arg 348 | Lys 348 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 43605.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 975.1 | |
| All* | Total formula weight | 44580.8 |
