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8W2T

Cryo-EM structure of human tankyrase 2 SAM-PARP filament - apo state (focused refinement map).

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(D, Q)
Poly [ADP-ribose] polymerase tankyrase-2polymer31735657.32UniProt (Q9H2K2)
Pfam (PF07647)
Pfam (PF00644)
Homo sapiens (human)ADP-ribosyltransferase diphtheria toxin-like 6,ARTD6,Poly [ADP-ribose] polymerase 5B,Protein poly-ADP-ribosyltransferase tankyrase-2,TNKS-2,TRF1-interacting ankyrin-related ADP-ribose polymerase 2,Tankyrase II,Tankyrase-2,TANK2,Tankyrase-like protein,Tankyrase-related protein
2C, D
(D, Q)
ZINC IONnon-polymer65.42Chemie (ZN)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight71314.7
Non-Polymers*Number of molecules2
Total formula weight130.8
All*Total formula weight71445.5
*Water molecules are not included.

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PDB entries from 2025-11-05

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