8W00

Q108K:K40L:T51V:T53S:Y19W:R58W:L117E mutant of hCRBPII bound to synthetic fluorophore TD-1V

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Retinol-binding protein 2	polymer	133	15634.5	2	UniProt (P50120) Pfam (PF00061) In PDB	Homo sapiens (human)	Cellular retinol-binding protein II,CRBP-II
2	A, B	(2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal	non-polymer		271.4	2	Chemie (A1AEQ)
3	A, B	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
4		water	water		18.0	185	Chemie (HOH)

Sequence modifications

A, B: 1 - 133 (UniProt: P50120)

PDB	External Database	Details
Trp 19	Tyr 20	engineered mutation
Leu 40	Lys 41	engineered mutation
Val 51	Thr 52	engineered mutation
Ser 53	Thr 54	engineered mutation
Trp 58	Arg 59	engineered mutation
Lys 108	Gln 109	engineered mutation
Glu 117	Leu 118	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	31269.0
Non-Polymers*	Number of molecules	4
	Total formula weight	660.8
All*	Total formula weight	31929.8

*Water molecules are not included.