8VZG
Carbonic anhydrase II mutant with DRD function
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Carbonic anhydrase 2 | polymer | 260 | 29316.1 | 1 | UniProt (P00918) Pfam (PF00194) | Homo sapiens (human) | Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II,Cyanamide hydratase CA2 |
| 2 | B (A) | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE | non-polymer | 222.2 | 1 | Chemie (AZM) | |||
| 3 | C (A) | CITRATE ANION | non-polymer | 189.1 | 1 | Chemie (FLC) | |||
| 4 | D, E, F (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | G, H (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | I (A) | water | water | 18.0 | 206 | Chemie (HOH) |
Sequence modifications
A: 1 - 260 (UniProt: P00918)
| PDB | External Database | Details |
|---|---|---|
| Asn 56 | Ser 56 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29316.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 818.4 | |
| All* | Total formula weight | 30134.5 |
