8VZF
Crystal Structure of 2-Hydroxyacyl-CoA Lyase/Synthase ApbHACS from Alphaproteobacteria bacterium in the Complex with THDP, Coenzyme A, and ADP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | 2-Hydroxyacyl-CoA Lyase/Synthase | polymer | 559 | 59788.0 | 4 | UniProt (A0A3C0TX30) In PDB | Alphaproteobacteria bacterium | |
2 | A, B, C, D | S-{(9R,13S,15R)-17-[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]-9,13,15-TRIHYDROXY-10,10-DIMETHYL-13,15-DIOXIDO-4,8-DIOXO-12,14,16-TRIOXA-3,7-DIAZA-13,15-DIPHOSPHAHEPTADEC-1-YL} THIOFORMATE | non-polymer | 795.5 | 4 | Chemie (FYN) | |||
3 | A, B, C, D | THIAMINE DIPHOSPHATE | non-polymer | 425.3 | 4 | Chemie (TPP) | |||
4 | D, A, B, C | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
5 | D, A, B, C | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 4 | Chemie (ADP) | |||
6 | D, A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
7 | A, C | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
8 | B, C | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
9 | C | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
10 | water | water | 18.0 | 336 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 554 (UniProt: A0A3C0TX30)
PDB | External Database | Details |
---|---|---|
Phe -4 | - | expression tag |
Gln -3 | - | expression tag |
Ser -2 | - | expression tag |
Asn -1 | - | expression tag |
Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 239152.1 | |
Non-Polymers* | Number of molecules | 27 |
Total formula weight | 7417.0 | |
All* | Total formula weight | 246569.1 |