8VZ4
L54G Mutant of E. coli Dihydrofolate Reductase Complexed with Nicotinamide Adenine Dinucleotide Phosphate (oxidized form)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dihydrofolate reductase | polymer | 159 | 17963.2 | 2 | UniProt (P0ABQ4) Pfam (PF00186) | Escherichia coli | |
| 2 | C, D (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 357 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 159 (UniProt: P0ABQ4)
| PDB | External Database | Details |
|---|---|---|
| Gly 54 | Leu 54 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35926.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1486.8 | |
| All* | Total formula weight | 37413.3 |
