8VXE
Structure of p38 alpha (Mitogen-activated protein kinase 14) complexed with inhibitor 6
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Mitogen-activated protein kinase 14 | polymer | 387 | 44657.7 | 1 | UniProt (Q16539) Pfam (PF00069) In PDB | Homo sapiens (human) | MAP kinase 14,MAPK 14,Cytokine suppressive anti-inflammatory drug-binding protein,CSAID-binding protein,CSBP,MAP kinase MXI2,MAX-interacting protein 2,Mitogen-activated protein kinase p38 alpha,MAP kinase p38 alpha,Stress-activated protein kinase 2a,SAPK2a |
2 | A | (4M)-4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridine | non-polymer | 292.3 | 2 | Chemie (A1AD9) | |||
3 | water | water | 18.0 | 151 | Chemie (HOH) |
Sequence modifications
A: 2 - 360 (UniProt: Q16539)
PDB | External Database | Details |
---|---|---|
Met -26 | - | initiating methionine |
Ser -25 | - | expression tag |
Tyr -24 | - | expression tag |
Tyr -23 | - | expression tag |
His -22 | - | expression tag |
His -21 | - | expression tag |
His -20 | - | expression tag |
His -19 | - | expression tag |
His -18 | - | expression tag |
His -17 | - | expression tag |
Asp -16 | - | expression tag |
Tyr -15 | - | expression tag |
Asp -14 | - | expression tag |
Ile -13 | - | expression tag |
Pro -12 | - | expression tag |
Thr -11 | - | expression tag |
Thr -10 | - | expression tag |
Glu -9 | - | expression tag |
Asn -8 | - | expression tag |
Leu -7 | - | expression tag |
Tyr -6 | - | expression tag |
Phe -5 | - | expression tag |
Gln -4 | - | expression tag |
Gly -3 | - | expression tag |
Ala -2 | - | expression tag |
Met -1 | - | expression tag |
Asp 0 | - | expression tag |
Pro 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 44657.7 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 584.6 | |
All* | Total formula weight | 45242.3 |