8VWT
OGG1 bound to a nucleosome containing 8oxoG at SHL-6 (composite map)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, E (E, A) | Histone H3.2 | polymer | 135 | 15257.8 | 2 | UniProt (Q71DI3) Pfam (PF00125) | Homo sapiens (human) | H3-clustered histone 13,H3-clustered histone 14,H3-clustered histone 15,Histone H3/m,Histone H3/o |
2 | B, F (F, B) | Histone H4 | polymer | 102 | 11263.2 | 2 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (human) | |
3 | C, G (G, C) | Histone H2A type 1 | polymer | 129 | 13990.3 | 2 | UniProt (P0C0S8) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (human) | H2A.1,Histone H2A/ptl |
4 | D, H (H, D) | Histone H2B type 1-C/E/F/G/I | polymer | 125 | 13806.0 | 2 | UniProt (P62807) Pfam (PF00125) | Homo sapiens (human) | Histone H2B.1 A,Histone H2B.a,H2B/a,Histone H2B.g,H2B/g,Histone H2B.h,H2B/h,Histone H2B.k,H2B/k,Histone H2B.l,H2B/l |
5 | I (I) | 601 I strand (non-damaged strand) | polymer | 147 | 45114.7 | 1 | synthetic construct | ||
6 | J (J) | 601 J strand (damaged strand) | polymer | 147 | 45651.1 | 1 | synthetic construct | ||
7 | K (K) | N-glycosylase/DNA lyase | polymer | 345 | 38833.1 | 1 | UniProt (O15527) Pfam (PF07934) Pfam (PF00730) | Homo sapiens (human) |
Sequence modifications
E, A: 1 - 135 (UniProt: Q71DI3)
K: 1 - 345 (UniProt: O15527)
PDB | External Database | Details |
---|---|---|
Ala 110 | Cys 111 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gln 249 | Lys 249 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 11 |
Total formula weight | 238233.8 | |
All* | Total formula weight | 238233.8 |