8VVM
Structure of FabS1CE1-EPR1-1 in complex with the erythropoietin receptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | S1CE1 VARIANT OF FAB-EPR-1 heavy chain | polymer | 224 | 24024.0 | 2 | Homo sapiens | ||
| 2 | G, C | S1CE1 VARIANT OF FAB-EPR-1 light chain | polymer | 212 | 23049.5 | 2 | Homo sapiens | ||
| 3 | I | Erythropoietin receptor | polymer | 232 | 25680.0 | 1 | UniProt (P19235) Pfam (PF09067) Pfam (PF00041) In PDB | Homo sapiens (human) | EPO-R |
| 4 | A, G, B, C | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 4 | Chemie (PEG) | |||
| 5 | A, B, C | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 6 | A, G, B, C | CHLORIDE ION | non-polymer | 35.5 | 7 | Chemie (CL) | |||
| 7 | C | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 8 | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
I: 1 - 226 (UniProt: P19235)
| PDB | External Database | Details |
|---|---|---|
| His 227 | - | expression tag |
| His 228 | - | expression tag |
| His 229 | - | expression tag |
| His 230 | - | expression tag |
| His 231 | - | expression tag |
| His 232 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 119826.9 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 826.7 | |
| All* | Total formula weight | 120653.6 |
