8VUU

Human GluN1-2B with Fab 007-168

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Glutamate receptor ionotropic, NMDA 1	polymer	819	92012.1	2	UniProt (Q05586) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) In PDB	Homo sapiens (human)	GluN1,Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1
2	B, D	Glutamate receptor ionotropic, NMDA 2B	polymer	815	91534.4	2	UniProt (Q13224) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) In PDB	Homo sapiens (human)	GluN2B,Glutamate [NMDA] receptor subunit epsilon-2,N-methyl D-aspartate receptor subtype 2B,NMDAR2B,NR2B,N-methyl-D-aspartate receptor subunit 3,NR3,hNR3
3	H, J	007-168 Heavy	polymer	211	22522.3	2		Homo sapiens
4	K, L	007-168 Light	polymer	215	23456.0	2		Homo sapiens

Sequence modifications

A, C: 23 - 838 (UniProt: Q05586)

PDB	External Database	Details
Asn 556	Gln 556	conflict
Ile 819	Leu 819	conflict
Ser 839	-	expression tag
Arg 840	-	expression tag
Ala 841	-	expression tag

B, D: 31 - 845 (UniProt: Q13224)

PDB	External Database	Details
Asp 348	Asn 348	conflict
Glu 354	Asp 354	conflict
Glu 437	Gln 437	conflict
Ser 838	Cys 838	conflict

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	459049.6
All*	Total formula weight	459049.6

*Water molecules are not included.