8VUU
Human GluN1-2B with Fab 007-168
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Glutamate receptor ionotropic, NMDA 1 | polymer | 819 | 92012.1 | 2 | UniProt (Q05586) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Homo sapiens (human) | GluN1,Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1 |
| 2 | B, D (B, D) | Glutamate receptor ionotropic, NMDA 2B | polymer | 815 | 91534.4 | 2 | UniProt (Q13224) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Homo sapiens (human) | GluN2B,Glutamate [NMDA] receptor subunit epsilon-2,N-methyl D-aspartate receptor subtype 2B,NMDAR2B,NR2B,N-methyl-D-aspartate receptor subunit 3,NR3,hNR3 |
| 3 | E, F (H, J) | 007-168 Heavy | polymer | 211 | 22522.3 | 2 | Homo sapiens | ||
| 4 | G, H (K, L) | 007-168 Light | polymer | 215 | 23456.0 | 2 | Homo sapiens |
Sequence modifications
A, C: 23 - 838 (UniProt: Q05586)
B, D: 31 - 845 (UniProt: Q13224)
| PDB | External Database | Details |
|---|---|---|
| Asn 556 | Gln 556 | conflict |
| Ile 819 | Leu 819 | conflict |
| Ser 839 | - | expression tag |
| Arg 840 | - | expression tag |
| Ala 841 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Asp 348 | Asn 348 | conflict |
| Glu 354 | Asp 354 | conflict |
| Glu 437 | Gln 437 | conflict |
| Ser 838 | Cys 838 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 459049.6 | |
| All* | Total formula weight | 459049.6 |
