8VUS
Human GluN1-2A with IgG 007-168
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (E, H) | 007-168 Heavy | polymer | 211 | 22522.3 | 2 | Homo sapiens | ||
| 2 | B, D (F, L) | 007-168 Light | polymer | 215 | 23456.0 | 2 | Homo sapiens | ||
| 3 | E (A) | Glutamate receptor ionotropic, NMDA 1 | polymer | 776 | 87477.8 | 1 | UniProt (Q05586) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Homo sapiens (human) | GluN1,Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1 |
| 4 | F, H (B, D) | Glutamate receptor ionotropic, NMDA 2A | polymer | 771 | 86507.9 | 2 | UniProt (A0A6P6HB11) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) UniProt (by SIFTS) (Q12879) | Homo sapiens (human) | |
| 5 | G (C) | Glutamate receptor ionotropic, NMDA 1 | polymer | 776 | 87534.9 | 1 | UniProt (Q05586) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Homo sapiens (human) | GluN1,Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1 |
Sequence modifications
B, D: 34 - 784 (UniProt: A0A6P6HB11)
C: 23 - 779 (UniProt: Q05586)
| PDB | External Database | Details |
|---|---|---|
| Met 39 | Leu 39 | conflict |
| Thr 53 | Asn 53 | conflict |
| His 119 | Gln 119 | conflict |
| Val 122 | Ile 122 | conflict |
| Glu 182 | Asp 182 | conflict |
| Val 187 | Ile 187 | conflict |
| Ile 296 | Leu 296 | conflict |
| Ser 304 | Tyr 304 | conflict |
| Met 324 | Thr 324 | conflict |
| Arg 326 | Lys 326 | conflict |
| Val 329 | Ala 329 | conflict |
| Met 331 | Pro 331 | conflict |
| Pro 336 | Gln 336 | conflict |
| His 381 | Gln 381 | conflict |
| Thr 382 | Ser 382 | conflict |
| Cys 542 | Ser 587 | conflict |
| Asp 542 | Lys 590 | conflict |
| Arg 542 | Lys 592 | conflict |
| Pro 543 | - | insertion |
| Gly 543 | - | insertion |
| Gly 543 | - | insertion |
| Pro 543 | - | insertion |
| Ser 543 | - | insertion |
| Phe 543 | - | insertion |
| Thr 543 | - | insertion |
| Ile 543 | - | insertion |
| Gly 543 | - | insertion |
| Lys 543 | - | insertion |
| Ala 543 | - | insertion |
| Ile 543 | - | insertion |
| Trp 543 | - | insertion |
| Leu 543 | - | insertion |
| Trp 543 | Thr 595 | conflict |
| Leu 543 | - | insertion |
| Val 543 | - | insertion |
| Phe 543 | - | insertion |
| Asn 543 | - | insertion |
| Asn 543 | - | insertion |
| Ser 543 | - | insertion |
| Val 543 | - | insertion |
| Pro 543 | - | insertion |
| Val 543 | - | insertion |
| Asn 544 | - | insertion |
| Pro 544 | - | insertion |
| Lys 544 | - | insertion |
| Gly 544 | - | insertion |
| Thr 544 | - | insertion |
| Thr 544 | - | insertion |
| Ser 544 | - | insertion |
| Lys 544 | - | insertion |
| Ile 544 | - | insertion |
| Met 544 | - | insertion |
| Val 544 | - | insertion |
| Ser 544 | - | insertion |
| Val 544 | - | insertion |
| Ala 544 | - | insertion |
| Phe 544 | - | insertion |
| Phe 544 | - | insertion |
| Ala 544 | - | insertion |
| Val 544 | - | insertion |
| Ile 544 | - | insertion |
| Phe 544 | - | insertion |
| Leu 544 | - | insertion |
| Ala 544 | - | insertion |
| Ser 544 | - | insertion |
| Tyr 544 | - | insertion |
| Thr 545 | - | insertion |
| Ala 545 | - | insertion |
| Asn 545 | - | insertion |
| Leu 545 | - | insertion |
| Ala 545 | - | insertion |
| Ala 545 | - | insertion |
| Phe 545 | - | insertion |
| Met 545 | - | insertion |
| Ile 545 | - | insertion |
| Gln 545 | - | insertion |
| Glu 545 | - | insertion |
| Glu 545 | - | insertion |
| Phe 545 | - | insertion |
| Val 639 | - | insertion |
| Asp 640 | - | insertion |
| Val 642 | - | insertion |
| Thr 643 | - | insertion |
| Gly 644 | - | insertion |
| Leu 645 | - | insertion |
| Ser 646 | - | insertion |
| Asp 647 | - | insertion |
| Lys 648 | - | insertion |
| Lys 649 | - | insertion |
| PDB | External Database | Details |
|---|---|---|
| Ala 54 | Gly 54 | conflict |
| Arg 358 | Asn 358 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 439985.0 | |
| All* | Total formula weight | 439985.0 |
