8VUR
Human GluN1-2A with IgG 003-102 WT conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glutamate receptor ionotropic, NMDA 1 | polymer | 815 | 91680.8 | 1 | UniProt (Q05586) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Homo sapiens (human) | GluN1,Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1 |
| 2 | B, D (B, D) | Glutamate receptor ionotropic, NMDA 2A | polymer | 808 | 90684.8 | 2 | UniProt (Q12879) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Homo sapiens (human) | GluN2A,Glutamate [NMDA] receptor subunit epsilon-1,N-methyl D-aspartate receptor subtype 2A,NMDAR2A,NR2A,hNR2A |
| 3 | C (C) | Glutamate receptor ionotropic, NMDA 1 | polymer | 815 | 91737.9 | 1 | UniProt (Q05586) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Homo sapiens (human) | GluN1,Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1 |
| 4 | E (H) | 003-102 Heavy | polymer | 234 | 25338.2 | 1 | Homo sapiens | ||
| 5 | F (L) | 003-102 Light | polymer | 218 | 23345.2 | 1 | Homo sapiens |
Sequence modifications
B, D: 34 - 814 (UniProt: Q12879)
C: 27 - 813 (UniProt: Q05586)
| PDB | External Database | Details |
|---|---|---|
| Cys 578 | Asn 587 | conflict |
| Asp 578 | Lys 590 | conflict |
| Arg 578 | Lys 592 | conflict |
| Glu 578 | Ala 593 | conflict |
| Gly 578 | His 595 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 54 | Gly 54 | conflict |
| Arg 358 | Asn 358 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 413471.7 | |
| All* | Total formula weight | 413471.7 |
