8VUH
Human GluN1-2A IgG 003-102 splayed conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glutamate receptor ionotropic, NMDA 1 | polymer | 815 | 91680.8 | 1 | UniProt (Q05586) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Homo sapiens (human) | GluN1,Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1 |
| 2 | B, D (B, D) | Glutamate receptor ionotropic, NMDA 2A | polymer | 808 | 90684.8 | 2 | UniProt (Q12879) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Homo sapiens (human) | GluN2A,Glutamate [NMDA] receptor subunit epsilon-1,N-methyl D-aspartate receptor subtype 2A,NMDAR2A,NR2A,hNR2A |
| 3 | C (C) | Glutamate receptor ionotropic, NMDA 1 | polymer | 816 | 91837.0 | 1 | UniProt (Q05586) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Homo sapiens (human) | GluN1,Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1 |
| 4 | E, F (H, I) | 003-102 Heavy | polymer | 117 | 12678.1 | 2 | Homo sapiens | ||
| 5 | G, H (L, M) | 003-102 Light | polymer | 109 | 11681.6 | 2 | Homo sapiens |
Sequence modifications
B, D: 34 - 814 (UniProt: Q12879)
C: 26 - 813 (UniProt: Q05586)
| PDB | External Database | Details |
|---|---|---|
| Cys 578 | Asn 587 | conflict |
| Asp 578 | Lys 590 | conflict |
| Arg 578 | Lys 592 | conflict |
| Glu 578 | Ala 593 | conflict |
| Gly 578 | His 595 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Arg 358 | Asn 358 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 413606.8 | |
| All* | Total formula weight | 413606.8 |
