8VSE

Cryo-EM structure of human CD45 extracellular region in complex with adenoviral protein E3/49K

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Receptor-type tyrosine-protein phosphatase C	polymer	551	60713.8	2	UniProt (P08575) Pfam (PF12567) Pfam (PF00041)	Homo sapiens (human)	Leukocyte common antigen,L-CA,T200
2	C (C)	45.5kDa protein	polymer	343	39408.9	1	UniProt (Q67812) Pfam (PF02440)	Human adenovirus 19a	E3 protein ( 49Kprotein )
3	D, E, F, G, H... (L, D, E, F, G...)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	6	In PDB GlyTouCan (G42666HT)
4	J (I)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
5	K, L, M, N, O (A, B, C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	5	Chemie (NAG)

Sequence modifications

C: 1 - 334 (UniProt: Q67812)

PDB	External Database	Details
Gly 335	-	expression tag
Ala 336	-	expression tag
Pro 337	-	expression tag
His 338	-	expression tag
His 339	-	expression tag
His 340	-	expression tag
His 341	-	expression tag
His 342	-	expression tag
His 343	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	160836.6
Branched	Number of molecules	7
	Total formula weight	3132.9
Non-Polymers*	Number of molecules	5
	Total formula weight	1106.0
All*	Total formula weight	165075.6

*Water molecules are not included.