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8VRA

Structure of a synthetic antibody in complex with a class I MHC presenting a hapten-peptide conjugate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
HLA class I histocompatibility antigen, A alpha chainpolymer27531758.01UniProt (P04439)
Pfam (PF00129)
Pfam (PF07654)
Homo sapiens (human)
2B
(B)
Beta-2-microglobulinpolymer9911748.21UniProt (P61769)
Pfam (PF07654)
Homo sapiens (human)
3C
(C)
GTPase KRas, N-terminally processedpolymer10889.11UniProt (P01116)Homo sapiens
4D
(D)
R023 Fab light chainpolymer21623518.21Homo sapiens
5E
(E)
R023 Fab heavy chainpolymer22824034.81Homo sapiens
6F
(D)
AMG 510 (bound form)non-polymer562.61Chemie (MOV)
Sequence modifications
C: 7 - 16 (UniProt: P01116)
PDBExternal DatabaseDetails
Cys 12Gly 12variant
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight91948.2
Non-Polymers*Number of molecules1
Total formula weight562.6
All*Total formula weight92510.8
*Water molecules are not included.

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PDB entries from 2024-11-06

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