8VPF
Structure of SARS-CoV spike in complex with CoV1-65 Fab (NTD-bound)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G (A, B, C) | Spike glycoprotein | polymer | 1249 | 138740.7 | 3 | UniProt (P59594) Pfam (PF16451) Pfam (PF09408) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus | S glycoprotein,E2,Peplomer protein |
| 2 | B, E, H (M, D, E) | CoV1-65 antibody heavy chain | polymer | 231 | 24347.4 | 3 | Homo sapiens (human) | ||
| 3 | C, F, I (N, F, G) | CoV1-65 antibody light chain | polymer | 217 | 22878.3 | 3 | Homo sapiens (human) | ||
| 4 | J, K, M, N, O... (H, I, K, L, O...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 9 | In PDB GlyTouCan (G42666HT) | |||
| 5 | L, P, T (J, P, T) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 6 | AA, BA, CA, DA, EA... (B, C, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 15 | Chemie (NAG) |
Sequence modifications
A, B, C: 1 - 1190 (UniProt: P59594)
| PDB | External Database | Details |
|---|---|---|
| Ala 577 | Ser 577 | variant |
| Pro 968 | Lys 968 | conflict |
| Pro 969 | Val 969 | conflict |
| Gly 1191 | - | expression tag |
| Ser 1192 | - | expression tag |
| Gly 1193 | - | expression tag |
| Tyr 1194 | - | expression tag |
| Ile 1195 | - | expression tag |
| Pro 1196 | - | expression tag |
| Glu 1197 | - | expression tag |
| Ala 1198 | - | expression tag |
| Pro 1199 | - | expression tag |
| Arg 1200 | - | expression tag |
| Asp 1201 | - | expression tag |
| Gly 1202 | - | expression tag |
| Gln 1203 | - | expression tag |
| Ala 1204 | - | expression tag |
| Tyr 1205 | - | expression tag |
| Val 1206 | - | expression tag |
| Arg 1207 | - | expression tag |
| Lys 1208 | - | expression tag |
| Asp 1209 | - | expression tag |
| Gly 1210 | - | expression tag |
| Glu 1211 | - | expression tag |
| Trp 1212 | - | expression tag |
| Val 1213 | - | expression tag |
| Leu 1214 | - | expression tag |
| Leu 1215 | - | expression tag |
| Ser 1216 | - | expression tag |
| Thr 1217 | - | expression tag |
| Phe 1218 | - | expression tag |
| Leu 1219 | - | expression tag |
| Gly 1220 | - | expression tag |
| Arg 1221 | - | expression tag |
| Ser 1222 | - | expression tag |
| Leu 1223 | - | expression tag |
| Glu 1224 | - | expression tag |
| Val 1225 | - | expression tag |
| Leu 1226 | - | expression tag |
| Phe 1227 | - | expression tag |
| Gln 1228 | - | expression tag |
| Gly 1229 | - | expression tag |
| Pro 1230 | - | expression tag |
| Gly 1231 | - | expression tag |
| His 1232 | - | expression tag |
| His 1233 | - | expression tag |
| His 1234 | - | expression tag |
| His 1235 | - | expression tag |
| His 1236 | - | expression tag |
| His 1237 | - | expression tag |
| His 1238 | - | expression tag |
| His 1239 | - | expression tag |
| Ser 1240 | - | expression tag |
| Ala 1241 | - | expression tag |
| Trp 1242 | - | expression tag |
| Ser 1243 | - | expression tag |
| His 1244 | - | expression tag |
| Pro 1245 | - | expression tag |
| Gln 1246 | - | expression tag |
| Phe 1247 | - | expression tag |
| Glu 1248 | - | expression tag |
| Lys 1249 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 557899.2 | |
| Branched | Number of molecules | 12 |
| Total formula weight | 5579.2 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3318.1 | |
| All* | Total formula weight | 566796.5 |
