8VNZ

PRC2_AJ1-450 bound to H3K36me3-modified nucleosome with histone H3 tail disengaged

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Polycomb protein SUZ12	polymer	739	83181.9	1	UniProt (Q15022) Pfam (PF09733)	Homo sapiens (human)	Chromatin precipitated E2F target 9 protein,ChET 9 protein,Joined to JAZF1 protein,Suppressor of zeste 12 protein homolog
2	B (L)	Polycomb protein EED	polymer	441	50267.7	1	UniProt (O75530) Pfam (PF00400)	Homo sapiens (human)	hEED,Embryonic ectoderm development protein,WD protein associating with integrin cytoplasmic tails 1,WAIT-1
3	C (N)	Histone-binding protein RBBP4	polymer	425	47709.5	1	UniProt (Q09028) Pfam (PF12265) Pfam (PF00400)	Homo sapiens (human)	Chromatin assembly factor 1 subunit C,CAF-1 subunit C,Chromatin assembly factor I p48 subunit,CAF-I 48 kDa subunit,CAF-I p48,Nucleosome-remodeling factor subunit RBAP48,Retinoblastoma-binding protein 4,RBBP-4,Retinoblastoma-binding protein p48
4	D (C)	Histone-lysine N-methyltransferase EZH2	polymer	746	85492.3	1	UniProt (Q15910) Pfam (PF11616) Pfam (PF18118) Pfam (PF21358) Pfam (PF18264) Pfam (PF00856)	Homo sapiens (human)	ENX-1,Enhancer of zeste homolog 2,Lysine N-methyltransferase 6
5	E (B)	Protein Jumonji	polymer	449	49174.9	1	UniProt (Q92833)	Homo sapiens (human)	Jumonji/ARID domain-containing protein 2
6	F (P)	Isoform 3 of Zinc finger protein AEBP2	polymer	301	34042.1	1	UniProt (Q6ZN18)	Homo sapiens (human)	Adipocyte enhancer-binding protein 2,AE-binding protein 2
7	G (C)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	1	Chemie (SAH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	349868.4
Non-Polymers*	Number of molecules	1
	Total formula weight	384.4
All*	Total formula weight	350252.9

*Water molecules are not included.