8VMG
Crystal structure of GSK-3 26-383 bound to Axin 383-435
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Glycogen synthase kinase-3 beta | polymer | 364 | 41538.7 | 2 | UniProt (Q9WV60) Pfam (PF00069) In PDB | Mus musculus (house mouse) | GSK-3 beta,Serine/threonine-protein kinase GSK3B |
2 | C, D | Axin-1 | polymer | 60 | 6657.3 | 2 | UniProt (O15169) In PDB | Homo sapiens (human) | Axis inhibition protein 1,hAxin |
3 | A | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
4 | A, B, C | 1,2-ETHANEDIOL | non-polymer | 62.1 | 39 | Chemie (EDO) | |||
5 | A | NITRATE ION | non-polymer | 62.0 | 8 | Chemie (NO3) | |||
6 | A | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
7 | C, A, B | SULFATE ION | non-polymer | 96.1 | 9 | Chemie (SO4) | |||
8 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
9 | C, D, A, B | CHLORIDE ION | non-polymer | 35.5 | 15 | Chemie (CL) | |||
10 | B | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
11 | water | water | 18.0 | 158 | Chemie (HOH) |
Sequence modifications
A, B: 26 - 383 (UniProt: Q9WV60)
C, D: 383 - 435 (UniProt: O15169)
PDB | External Database | Details |
---|---|---|
His 384 | - | expression tag |
His 385 | - | expression tag |
His 386 | - | expression tag |
His 387 | - | expression tag |
His 388 | - | expression tag |
His 389 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 376 | - | expression tag |
Gly 377 | - | expression tag |
Trp 378 | - | expression tag |
Gly 379 | - | expression tag |
Ser 380 | - | expression tag |
Gly 381 | - | expression tag |
Gly 382 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 96392.0 | |
Non-Polymers* | Number of molecules | 78 |
Total formula weight | 5328.2 | |
All* | Total formula weight | 101720.1 |