8VM1
Structural Elucidation of the Mesothelin Mucin16 CA125 Interaction
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mesothelin, cleaved form,Mucin-16 | polymer | 192 | 21898.0 | 1 | UniProt (Q13421) UniProt (Q8WXI7) Pfam (PF01390) | Homo sapiens (human) | MUC-16,Ovarian cancer-related tumor marker CA125,CA-125,Ovarian carcinoma antigen CA125 |
| 2 | B (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | C (B) | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G62182OO) | |||
| 4 | D (A) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A: -2 - 61 (UniProt: Q13421)
A: 62 - 187 (UniProt: Q8WXI7)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21898.0 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1010.9 | |
| All* | Total formula weight | 22908.9 |
