8VLL
Crystal structure of the yeast cytosine deaminase (yCD) M100W mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Cytosine deaminase | polymer | 161 | 17867.3 | 2 | UniProt (Q12178) In PDB | Saccharomyces cerevisiae (brewer's yeast) | yCD,Cytosine aminohydrolase,Fluorocytosine resistance protein 1 |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 4 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 5 | water | water | 18.0 | 214 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 158 (UniProt: Q12178)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Trp 100 | Met 100 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35734.6 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 722.3 | |
| All* | Total formula weight | 36457.0 |
