8VLK
Crystal structure of the yeast cytosine deaminase containing both open and closed active sites
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Cytosine deaminase | polymer | 161 | 17812.3 | 4 | UniProt (Q12178) Pfam (PF00383) | Saccharomyces cerevisiae (brewer's yeast) | yCD,Cytosine aminohydrolase,Fluorocytosine resistance protein 1 |
| 2 | E, F, I, J, N... (A, B, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 3 | G, K, L, P (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | H, M (A, C) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 411 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 158 (UniProt: Q12178)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 71249.2 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 826.2 | |
| All* | Total formula weight | 72075.4 |
