8VLJ
Crystal structure of the cacodylate-bound yeast cytosine deaminase (closed form)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cytosine deaminase | polymer | 161 | 17812.3 | 2 | UniProt (Q12178) Pfam (PF00383) | Saccharomyces cerevisiae (brewer's yeast) | yCD,Cytosine aminohydrolase,Fluorocytosine resistance protein 1 |
| 2 | C, G (A, B) | CACODYLATE ION | non-polymer | 137.0 | 2 | Chemie (CAC) | |||
| 3 | D, E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | F, H (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | I (B) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 312 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 158 (UniProt: Q12178)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35624.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 551.9 | |
| All* | Total formula weight | 36176.5 |
