8VKB
Crystal structure of Plasmodium vivax glycylpeptide N-tetradecanoyltransferase (N-myristoyltransferase, NMT) bound to myristoyl-CoA and inhibitor 10b
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Glycylpeptide N-tetradecanoyltransferase | polymer | 386 | 45100.6 | 3 | UniProt (A5K1A2) In PDB | Plasmodium vivax Sal-1 | |
| 2 | A, B, C | TETRADECANOYL-COA | non-polymer | 977.9 | 3 | Chemie (MYA) | |||
| 3 | A, B, C | {1,5-dimethyl-4-[2-({(1P)-1-[2-(piperazin-1-yl)pyridin-4-yl]naphthalen-2-yl}oxy)ethyl]-1H-pyrazol-3-yl}(morpholin-4-yl)methanone | non-polymer | 540.7 | 3 | Chemie (A1AB8) | |||
| 4 | C, A, B | CHLORIDE ION | non-polymer | 35.5 | 18 | Chemie (CL) | |||
| 5 | C, A, B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 6 | A | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 1 | Chemie (1PE) | |||
| 7 | B | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 1 | Chemie (P6G) | |||
| 8 | water | water | 18.0 | 620 | Chemie (HOH) |
Sequence modifications
A, B, C: 27 - 410 (UniProt: A5K1A2)
| PDB | External Database | Details |
|---|---|---|
| Gly 25 | - | expression tag |
| Pro 26 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 135301.7 | |
| Non-Polymers* | Number of molecules | 29 |
| Total formula weight | 5990.7 | |
| All* | Total formula weight | 141292.4 |
