8VJD
Human R14A Pin1 covalently bound to inhibitor 158F10 in P21 21 21 space group
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | polymer | 166 | 18467.5 | 2 | UniProt (Q13526) Pfam (PF00397) Pfam (PF00639) | Homo sapiens (human) | Peptidyl-prolyl cis-trans isomerase Pin1,PPIase Pin1,Rotamase Pin1 |
| 2 | C, D (C, D) | Inhibitor 158F10 | polymer | 5 | 516.6 | 2 | synthetic construct | ||
| 3 | E, L (A, B) | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL | non-polymer | 326.4 | 2 | Chemie (P33) | |||
| 4 | F, G, H, I, J... (A, B) | SULFATE ION | non-polymer | 96.1 | 9 | Chemie (SO4) | |||
| 5 | P, Q, R, S (A, B, C, D) | water | water | 18.0 | 265 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 163 (UniProt: Q13526)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 14 | Arg 14 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 37968.2 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1517.3 | |
| All* | Total formula weight | 39485.5 |
