8VIZ

Structure of full-length gelsolin bound to the barbed end of F-actin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Actin, alpha skeletal muscle	polymer	375	41875.6	6	UniProt (P68135) Pfam (PF00022)	Oryctolagus cuniculus (rabbit)	Alpha-actin-1
2	G (G)	Gelsolin	polymer	746	82737.7	1	UniProt (P06396) Pfam (PF00626)	Homo sapiens (human)	AGEL,Actin-depolymerizing factor,ADF,Brevin
3	H, J, L, N, P (A, B, C, D, E)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	5	Chemie (ADP)
4	AA, I, K, M, O... (G, A, B, C, D...)	CALCIUM ION	non-polymer		40.1	14	Chemie (CA)
5	R (F)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	1	Chemie (ATP)

Sequence modifications

G: 25 - 755 (UniProt: P06396)

PDB	External Database	Details
Met 18	-	initiating methionine
His 19	-	expression tag
His 20	-	expression tag
His 21	-	expression tag
His 22	-	expression tag
His 23	-	expression tag
His 24	-	expression tag
Trp 756	-	expression tag
Ser 757	-	expression tag
His 758	-	expression tag
Pro 759	-	expression tag
Gln 760	-	expression tag
Phe 761	-	expression tag
Glu 762	-	expression tag
Lys 763	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	333991.5
Non-Polymers*	Number of molecules	20
	Total formula weight	3204.3
All*	Total formula weight	337195.8

*Water molecules are not included.