8VHQ
Crystal structure of E. coli class Ia ribonucleotide reductase alpha subunit W28A variant bound to dATP and ATP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Ribonucleoside-diphosphate reductase 1 subunit alpha | polymer | 779 | 87682.0 | 4 | UniProt (P00452) Pfam (PF03477) Pfam (PF00317) Pfam (PF02867) In PDB | Escherichia coli K-12 | Protein B1,Ribonucleoside-diphosphate reductase 1 R1 subunit,Ribonucleotide reductase 1 |
2 | A, B, C, D | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE | non-polymer | 491.2 | 8 | Chemie (DTP) | |||
3 | A, B, C, D | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
4 | A, B, C, D | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 4 | Chemie (ATP) |
Sequence modifications
A, B, C, D: 1 - 760 (UniProt: P00452)
PDB | External Database | Details |
---|---|---|
Met -18 | - | initiating methionine |
Gly -17 | - | expression tag |
Ser -16 | - | expression tag |
Ser -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
Ser -8 | - | expression tag |
Ser -7 | - | expression tag |
Gly -6 | - | expression tag |
Leu -5 | - | expression tag |
Val -4 | - | expression tag |
Pro -3 | - | expression tag |
Arg -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Ala 28 | Trp 28 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 350728.0 | |
Non-Polymers* | Number of molecules | 20 |
Total formula weight | 6152.6 | |
All* | Total formula weight | 356880.7 |