8VHH
Engineered holo tryptophan synthase (Tm9D8*) derived from T. maritima TrpB
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Tryptophan synthase beta chain 1 | polymer | 397 | 43955.2 | 2 | UniProt (P50909) Pfam (PF00291) In PDB | Thermotoga maritima | |
2 | A, B | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 2 | Chemie (PLP) | |||
3 | A, B | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
4 | A, B | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
5 | water | water | 18.0 | 94 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 389 (UniProt: P50909)
PDB | External Database | Details |
---|---|---|
Gly 19 | Pro 19 | engineered mutation |
Gly 30 | Glu 30 | engineered mutation |
Val 69 | Ile 69 | engineered mutation |
Leu 96 | Lys 96 | engineered mutation |
Leu 140 | Pro 140 | engineered mutation |
Asp 167 | Asn 167 | engineered mutation |
Phe 184 | Ile 184 | engineered mutation |
Pro 213 | Leu 213 | engineered mutation |
Ser 228 | Gly 228 | engineered mutation |
Ser 292 | Thr 292 | engineered mutation |
Leu 390 | - | expression tag |
Glu 391 | - | expression tag |
His 392 | - | expression tag |
His 393 | - | expression tag |
His 394 | - | expression tag |
His 395 | - | expression tag |
His 396 | - | expression tag |
His 397 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 87910.3 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 857.4 | |
All* | Total formula weight | 88767.7 |