8VGH

CryoEM structure of tryptase in complex with wild type anti-tryptase Fab E104.v1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Tryptase alpha/beta-1	polymer	260	29211.1	4	UniProt (Q15661) Pfam (PF00089)	Homo sapiens (human)	Tryptase-1,Tryptase I,Tryptase alpha-1
2	E, J, K, L (G, E, I, L)	Fab E104.v1 light chain	polymer	217	23601.2	4		Homo sapiens (human)
3	F, G, H, I (H, F, J, K)	Fab E104.v1 heavy chain	polymer	230	24232.3	4		Homo sapiens (human)

Sequence modifications

A, B, C, D: 16 - 247 (UniProt: Q15661)

PDB	External Database	Details
Ala 1	-	expression tag
Gly 2	-	expression tag
Ser 3	-	expression tag
Thr 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
Asp 11	-	expression tag
Asp 12	-	expression tag
Asp 13	-	expression tag
Asp 14	-	expression tag
Lys 15	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	308178.1
All*	Total formula weight	308178.1

*Water molecules are not included.