8VFZ
Cryo-EM structure of FoxA1 in complex with ALBN1 nucleosome (class 2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (O, P) | Hepatocyte nuclear factor 3-alpha | polymer | 478 | 50022.6 | 2 | UniProt (P55317) Pfam (PF08430) Pfam (PF00250) Pfam (PF09354) | Homo sapiens (human) | HNF-3-alpha,HNF-3A,Forkhead box protein A1,Transcription factor 3A,TCF-3A |
| 2 | B (I) | DNA (171-MER) | polymer | 186 | 57399.6 | 1 | synthetic construct | ||
| 3 | C (J) | DNA (171-MER) | polymer | 186 | 57427.8 | 1 | synthetic construct | ||
| 4 | E, H (G, C) | Histone H2A type 1-B/E | polymer | 130 | 14165.6 | 2 | UniProt (P04908) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (human) | Histone H2A.2,Histone H2A/a,Histone H2A/m |
| 5 | F, J (A, E) | Histone H3.1 | polymer | 136 | 15437.2 | 2 | UniProt (P68431) Pfam (PF00125) | Homo sapiens (human) | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
| 6 | G, K (B, F) | Histone H4 | polymer | 103 | 11394.4 | 2 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (human) | |
| 7 | I, L (D, H) | Histone H2B type 1-J | polymer | 126 | 13935.2 | 2 | UniProt (P06899) Pfam (PF00125) | Homo sapiens (human) | Histone H2B.1,Histone H2B.r,H2B/r |
Sequence modifications
O, P: 1 - 472 (UniProt: P55317)
| PDB | External Database | Details |
|---|---|---|
| His 473 | - | expression tag |
| His 474 | - | expression tag |
| His 475 | - | expression tag |
| His 476 | - | expression tag |
| His 477 | - | expression tag |
| His 478 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 324737.3 | |
| All* | Total formula weight | 324737.3 |
